Choriocarcinoma in a Twenty Four Month Old Child : A Case Report
Choriocarcinoma in a Twenty Four Month Old Child : A Case Report

Keywords

Choriocarcinoma
Non-gestational
Trophoblastic cells
neoplasm

Abstract

Choriocarcinoma is a progressive malignant
neoplasm of trophoblastic cells. It is of two types:
gestational or non-gestational choriocarcinoma.
Gestational choriocarcinoma is derived from
placental trophoblast and non-gestational
choriocarcinoma is derived from germ cells. The
hematogenous spread is common in the lungs,
liver, brain, and other visceral organs. The
incidence of germ cell tumors in children is rare.
In this case study, we report a case of a two years
old child with a germ cell tumor, choriocarcinoma
based on microscopic and laboratory findings.
The majority of studies have suggested that the
diagnosis of pure non-gestational choriocarcinoma
should be limited to premenarcheal patients.
Timely diagnosis and the use of chemotherapy can
lead to a better survival rate.

 

Choriocarcinoma in a Twenty Four Month Old Child : A Case Report

References

1. Desai, N. R., Gupta, S., Said, R., Desai, P. &
Dai, Q. Choriocarcinoma in a 73-year-old woman:
A case report and review of the literature. J. Med.
Case Rep. 4, 2–6 (2010).
2. Dilek, S., Pata, Ö., Tok, E. & Polat, A.
Extraovarian nongestational choriocarcinoma in a
postmenopausal woman. Int. J. Gynecol. Cancer
14, 1033–1035 (2004).
3. Whaley, R. D., Dougherty, R. E., Cheng, L. &
Ulbright, T. M. Fluorescence In Situ Hybridization
for the X and Y Chromosome Centromeres
Helps Differentiate Between Gestational and
Nongestational Choriocarcinoma in Clinically
Ambiguous Cases. Arch. Pathol. Lab. Med. 144,
863–868 (2020).
4. Salazar-Mejía, C. E. et al. Choriocarcinoma
Syndrome as an Initial Presentation of Testicular
Cancer. Case Rep. Oncol. Med. 2018, 1–3 (2018).
5. Çorakçi, A. et al. Pure nongestational
choriocarcinoma of ovary. Arch. Gynecol. Obstet.
271, 176–177 (2005).
6. Lv, L., Yang, K., Wu, H., Lou, J. & Peng, Z.
Pure choriocarcinoma of the ovary: A case report. J.
Gynecol. Oncol. 22, 135–139 (2011).
7. Rawal, G., Ahluwalia, C., Yadav, A. K.
& Dhawan, I. Case Report Primary pure nongestational choriocarcinoma of ovary : a rare case
report. 6, 4166–4169 (2017).
8. Hayashi, S. et al. Primary non-gestational
pure choriocarcinoma arising in the ovary: A case
report and literature review. Oncol. Lett. 9, 2109–
2111 (2015).
9. Lee, S.-C. et al. Mixed Testicular Germ
Cell Tumor Presenting as Metastatic Pure
Choriocarcinoma Involving Multiple Lung
Metastases That Was Effectively Treated with
High-dose Chemotherapy. Cancer Res. Treat. 41,
229 (2009).
10. Choi, Y. J., Chun, K. Y., Kim, Y. W. & Ro,
D. Y. Pure nongestational choriocarcinoma of the
ovary: A case report. World J. Surg. Oncol. 11, 2–4
(2013).
11. Seppälä, M., Bagshawe, K. D. & Ruoslahti,
E. Radioimmunoassay of alpha‐fetoprotein: A
contribution to the diagnosis of choriocarcinoma
and hydatidiform mole. Int. J. Cancer 10, 478–481
(1972)

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