Abstract
Objective:
To evaluate the efficacy of tamsulosin in the treatment of distal
ureteric calculi.
Materials and Methods:
Forty patients, who meet the inclusion criteria, were selected for the prospective study. All these patients received tamsulosin 0.4 mg once before bed time for fourteen days to observe
the effectiveness, side effects and stone expulsion rate.
Results:
The average
time of stone expulsion was 8.03±2.80 days. The successful medical expulsion was seen in 82.50%. About 7.5% complained of dizziness and headache,
2.5% complained of fatigue and postural hypotension.
Conclusion:
The use
of tamsulosin was safe, effective and was associated with fewer side effects.
Successful stone expulsion rate was observed in in selected cases.
References
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2. Smith RD, Shah M, Patel A. Recent advances in
management of ureteral calculi. F1000 Med Rep.
2009 Jul; 1:53.
3. Finlayson B, Ackermann D. Overview of surgical
treatment of urolithiasis with special reference to
lithotripsy. J Urol. 1989 Mar; 141(3 Pt 2):778-9.
4. Nakada SY. Tamsulosin: ureteric motility. BJU Int.
2008 May;101(9):1061-2.
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of calcium-channel and alpha(1)-adrenoceptor antagonism on human ureteric activity. BJU Int. 2006
Sept;98:651–5.
6. Davenport K, Timoney AG, Keeley FX. Effect of
smooth muscle relaxant drugs on proximal human
ureteric activity in vivo: a pilot study. Urol Res.
2007 Aug;35(4):207-13.
7. Segura JW, Preminger GM, Assimos DG, Dretler
SP, Kahn RI, Lingeman JE, et al. Ureteral Stones
Clinical Guidelines Panel summary report on the
management of ureteral calculi. The American Urological Association .J Urol. 1997 Nov;158(5):1915-
21.
8. Al-Ansari A, Al-Naimi A, Alobaidy A, Assadiq K,
Azmi MD,Shokeir AA. Efficacy of tamsulosin in
the management of lower ureteral stones: a randomized double-blind placebo-controlled study of 100
patients. Urology. 2010 Jan;75(1):4-7.
9. Abdel-Meguid TA, Tayib A, Al-Sayyad A. Tamsulosin to treat uncomplicated distal ureteral calculi:
a double blind randomized placebo-controlled trial.
Can J Urol. 2010 Jun;17(3):5178-83.
10. Agrawal M, Gupta M, Gupta A, Agrawal A, Sarkari A, Lavania P. Prospective randomized trial comparing efficacy of alfuzosin and tamsulosin inmanagement of lower ureteral stones. Urology. 2009
Apr;73(4):706-9
11. Bensalah K, Pearle M, Lotan Y. Cost-effectiveness
of medical expulsive therapy using alpha-blockers for the treatment of distal ureteral stones. Euro
Urology. 2008 Feb;53(2):411-8.
12. Cooper JT, Stack GM, Cooper TP. Intensive medical management of ureteral calculi. Urology. 2000
Oct;56(4):575-8.
13. Porpiglia F, Ghignone G, Fiori C, Fontana D, Scarpa RM. Nifedipine versus tamsulosin for the management of lower ureteral stones. J Urol. 2004
Aug;172(2):568-71.
14. Malin JM Jr, Deane RF, Boyarsky S. Characterisation of adrenergic receptors in human ureter. Br J
Urol. 1970 Jun;42:171-4.
15. Tzortzis V, Mamoulakis C, Rioja J, Gravas S,
Michel MC, de la Rosette JJ. Medical expulsive
therapy for distal ureteral stones. Drugs. 2009
April;69(6):677–92.
16. Dellabella M, Milanese G, Muzzonigro G. Efficacy
of tamsulosin in the medical management of juxta
vesical ureteral stones. J Urol. 2003 Dec;170(6 Pt
1):2202-5.
17. Kaneko T, Matsushima H, Morimoto H, Tsuzaka Y,
Homma Y. Efficacy of low dose tamsulosin in medical expulsive therapy for ureteral stones in Japanese male patients: A randomized controlled study.
Int J Urol. 2010 Feb;17:462-5.
18. Pickard R, Starr K, MacLennan G, Lam T, Thomas R, Burr J, et al. Medical expulsive therapy
in adults with ureteric colic: a multicentre,randomised, placebo-controlled trial. Lancet. 2015
Jul;386(9991):341–9.
19. Pricop C, Novac C, Negru D, ILie C, Pricop A, Tanase V. Can selective alpha blockers help the spontaneous passage of the stones located in the uretero bladder junction?. Rev Med Chir Soc Med Nat.
2004 Jan;108(1):128-33.
20. Lotan Y, Gettman MT, Roehrborn CG, Cadeddu
JA, Pearle MS. Management of ureteral calculi: A
cost comparison and decision making analysis. J
Urol. 2002 Apr;167(4):1621–9.
Jun;351(9118):1797-01.
2. Smith RD, Shah M, Patel A. Recent advances in
management of ureteral calculi. F1000 Med Rep.
2009 Jul; 1:53.
3. Finlayson B, Ackermann D. Overview of surgical
treatment of urolithiasis with special reference to
lithotripsy. J Urol. 1989 Mar; 141(3 Pt 2):778-9.
4. Nakada SY. Tamsulosin: ureteric motility. BJU Int.
2008 May;101(9):1061-2.
5. Davenport K, Timoney AG, Keeley FX. A comparative in vitro study to determine the beneficial effect
of calcium-channel and alpha(1)-adrenoceptor antagonism on human ureteric activity. BJU Int. 2006
Sept;98:651–5.
6. Davenport K, Timoney AG, Keeley FX. Effect of
smooth muscle relaxant drugs on proximal human
ureteric activity in vivo: a pilot study. Urol Res.
2007 Aug;35(4):207-13.
7. Segura JW, Preminger GM, Assimos DG, Dretler
SP, Kahn RI, Lingeman JE, et al. Ureteral Stones
Clinical Guidelines Panel summary report on the
management of ureteral calculi. The American Urological Association .J Urol. 1997 Nov;158(5):1915-
21.
8. Al-Ansari A, Al-Naimi A, Alobaidy A, Assadiq K,
Azmi MD,Shokeir AA. Efficacy of tamsulosin in
the management of lower ureteral stones: a randomized double-blind placebo-controlled study of 100
patients. Urology. 2010 Jan;75(1):4-7.
9. Abdel-Meguid TA, Tayib A, Al-Sayyad A. Tamsulosin to treat uncomplicated distal ureteral calculi:
a double blind randomized placebo-controlled trial.
Can J Urol. 2010 Jun;17(3):5178-83.
10. Agrawal M, Gupta M, Gupta A, Agrawal A, Sarkari A, Lavania P. Prospective randomized trial comparing efficacy of alfuzosin and tamsulosin inmanagement of lower ureteral stones. Urology. 2009
Apr;73(4):706-9
11. Bensalah K, Pearle M, Lotan Y. Cost-effectiveness
of medical expulsive therapy using alpha-blockers for the treatment of distal ureteral stones. Euro
Urology. 2008 Feb;53(2):411-8.
12. Cooper JT, Stack GM, Cooper TP. Intensive medical management of ureteral calculi. Urology. 2000
Oct;56(4):575-8.
13. Porpiglia F, Ghignone G, Fiori C, Fontana D, Scarpa RM. Nifedipine versus tamsulosin for the management of lower ureteral stones. J Urol. 2004
Aug;172(2):568-71.
14. Malin JM Jr, Deane RF, Boyarsky S. Characterisation of adrenergic receptors in human ureter. Br J
Urol. 1970 Jun;42:171-4.
15. Tzortzis V, Mamoulakis C, Rioja J, Gravas S,
Michel MC, de la Rosette JJ. Medical expulsive
therapy for distal ureteral stones. Drugs. 2009
April;69(6):677–92.
16. Dellabella M, Milanese G, Muzzonigro G. Efficacy
of tamsulosin in the medical management of juxta
vesical ureteral stones. J Urol. 2003 Dec;170(6 Pt
1):2202-5.
17. Kaneko T, Matsushima H, Morimoto H, Tsuzaka Y,
Homma Y. Efficacy of low dose tamsulosin in medical expulsive therapy for ureteral stones in Japanese male patients: A randomized controlled study.
Int J Urol. 2010 Feb;17:462-5.
18. Pickard R, Starr K, MacLennan G, Lam T, Thomas R, Burr J, et al. Medical expulsive therapy
in adults with ureteric colic: a multicentre,randomised, placebo-controlled trial. Lancet. 2015
Jul;386(9991):341–9.
19. Pricop C, Novac C, Negru D, ILie C, Pricop A, Tanase V. Can selective alpha blockers help the spontaneous passage of the stones located in the uretero bladder junction?. Rev Med Chir Soc Med Nat.
2004 Jan;108(1):128-33.
20. Lotan Y, Gettman MT, Roehrborn CG, Cadeddu
JA, Pearle MS. Management of ureteral calculi: A
cost comparison and decision making analysis. J
Urol. 2002 Apr;167(4):1621–9.
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